Which layer of skin contains nerves but lacks blood vessels?

The epidermis is the outermost layer of the skin and is primarily made up of keratinized cells. One of its distinctive features is that it does not contain any blood vessels. Instead, the epidermis receives nutrients and oxygen through diffusion from the underlying dermis, which is rich in blood supply. The presence of nerve endings within the epidermis allows for sensory perception, but the absence of blood vessels is a defining characteristic that differentiates it from the dermis and other deeper layers of the skin. This adaptability allows the skin to serve as a protective barrier while still enabling it to sense touch, pressure, and temperature changes.